Recent cyberattacks on healthcare facilities have had significant effects on every aspect of patient care and organizational continuity. They highlight the need for healthcare organizations of all sizes and types to implement cybersecurity best practices and conduct robust planning and exercising for cyber incident response and consequence management. As the number of cyberattacks on this sector increases, healthcare practitioners, facility executives, information technology professionals, and emergency managers must remain current on the ever-changing nature and type of threats to their facilities, systems, patients, and staff. The resources in this Topic Collection can help stakeholders better protect against, mitigate, respond to, and recover from cyber threats, ensuring patient safety and operational continuity.